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Growth Hormone
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CJC-1295 (no DAC)

Also known as: CJC

Molecular Weight

3367.97 Da

Half-Life

30 minutes (no DAC) / 5.8-8.1 days (with DAC)

Administration

Subcutaneous injection

Longevity Score

8/10

Mechanism of Action

A long-acting GHRH analog that produces dose-dependent increases in mean plasma GH concentrations (2-10 fold for 6+ days) and IGF-I levels (1.5-3 fold for 9-11 days). After multiple doses, IGF-I remains elevated for up to 28 days. Synergistic with GHRP peptides.

Research-Backed Benefits

  • Enhanced GH pulse amplitude (2-10x)
  • Sustained IGF-1 elevation (9-11 days per injection)
  • Body composition improvement
  • Anti-aging effects
  • Cumulative effect with repeated dosing

Dosing Protocols

beginner

100mcg before bed (30µg/kg)

intermediate

200mcg before bed (60µg/kg)

advanced

200mcg 2x daily

athlete

200mcg before bed with Ipamorelin

Frequency: Daily (before bed) · Duration: 8–16 weeks continuous; best combined with Ipamorelin on same schedule

Expected Results Timeline

Week 1-2

Enhanced sleep quality, GH elevation

Week 3-4

Improved recovery and energy, IGF-1 sustained

Week 5-8

Body composition changes

Long Term

Sustained GH optimization, cumulative IGF-1 benefits

Safety & Risks

  • Flushing sensation
  • Water retention
  • Requires fasted administration

Notable Research

CJC-1295 pharmacokinetics study (2006)

Produced sustained 2-10 fold elevation in GH and 1.5-3 fold IGF-1 increase

DOI: 10.1210/jc.2005-2664

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Research Disclaimer: This information is compiled from published research and is provided for educational purposes only. Peptides discussed here are classified as research chemicals in most jurisdictions and are not FDA-approved for human use unless otherwise noted. Consult a qualified healthcare provider before starting any protocol.